About CellType
CellType is building foundation models and agent systems for biology.
About the role
CellType is building foundation models and agent systems for biology.
We believe the next major advances in biotech AI will come from models trained to reason over biological data, experiments, and translational outcomes. We work with pharma and biotech partners on problems such as preclinical-to-clinical translation, response prediction, biomarker discovery, and scientific reasoning across complex biological datasets.
We are building the core intelligence layer for biology.
About the role: We are hiring a Founding Research Engineer to build and scale the systems that improve our models.
This role sits at the boundary of research and engineering. You will work on training, post-training, evaluation, performance optimization, and the systems needed to support all of that. You should be excited by both novel model development and the operational reality of making training systems run reliably.
This role is based in New York City. For exceptional candidates, we're willing to consider remote arrangements.
Responsibilities
- Build and improve training and post-training systems for biological foundation models and agentic model workflows.
- Design and run experiments across supervised fine-tuning, reinforcement learning, tool use, evaluation, and model behavior optimization.
- Build and maintain distributed RL and post-training infrastructure.
- Improve reliability of rollout, evaluation, and reward pipelines.
- Own critical parts of the model training stack, including performance, reliability, observability, and debugging.
- Investigate and resolve issues across the full stack, from training dynamics and evaluation infrastructure to distributed systems and hardware bottlenecks.
- Profile and eliminate performance bottlenecks across GPU, networking, and storage layers.
- Build clean abstractions for experiments, model evaluation, and distributed training workflows. Improve training efficiency, stability, and throughput.
- Work closely with founders and domain experts to translate biological problems into model tasks, environments, and evaluation frameworks.
- Help turn research improvements into real product and customer advantage.
- This role will directly shape the quality and speed of CellType's core model systems. The right person will help determine not only how good our models become, but how fast we can improve them and how confidently we can deploy them.
Requirements
- Have hands-on experience training or materially improving serious LLM or generative ML systems.
- Have strong software engineering and distributed systems fundamentals.
- Have deep experience with Python and modern ML frameworks such as PyTorch, JAX, or equivalent systems.
- Have experience with reinforcement learning or post-training methods.
- Have built evaluation systems for tool-using or open-ended models.
- Have a deep understanding of GPU execution constraints and memory trade-offs.
- Have experience debugging performance issues in production ML systems.
- Can reason about system-level trade-offs between latency, throughput, and cost.
- Have a track record of owning critical production infrastructure.
- Can balance research exploration with engineering implementation.
- Have experience with distributed systems, large-scale training, or performance-sensitive ML workloads.
- Care about code quality, testing, performance, and maintainability.
- Are comfortable in a small team where priorities move toward whatever is most important.
- Communicate clearly and collaborate well under both normal and high-pressure conditions.
- Want broad ownership rather than a narrow role boundary.
Nice to have
- Machine Learning
- Python
- PyTorch
- JAX
